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Time-Resolved Circular Dichroism: What Can We Learn on Conformational Changes?
François Hache

Time-resolved circular dichroism (CD) measurements can yield relevant information on the dynamics of conformational changes in molecules on the condition that some a priori knowledge is obtained. This can be the use of simple models such as the excitonic coupling or the octant rule or the phenomenological relationship between far-UV CD and secondary structures in proteins for example. This article describes such experiments where CD has brought relevant conformational information.

Keywords: Circular dichroism, conformational dynamics, proteins, protein folding

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