Application of FRET to Detect Drugs and Pollution
Zaid M Abdul Khalik, Zeyad A Saleh and Mazin A A. Ali
The Forster resonance energy transfer (FRET), including alterations in the interactions of electrons between an acceptor and a donor, is used in a variety of applications: in medicine, pharmacology, physiology, and biology. Since the first workshop some 50 years ago, the use of FRET is expanded to new applications, in drug discovery and biomedical research. The present review discusses the application of FRET in drug studies. The mechanism of photo-induced electron transfer is used for Cefixime and to determine the properties of Acetaminophen. In particular, it is used for measurable observing of the disaccharide and pentose gathering in the bacteria (E. coli). The Forster resonance energy transfer is also applied for recognition of pollution/contamination of water by arsenic.
Keywords: Forster resonance energy transfer, Cefixime, Acetaminophen, E. coli, arsenic in water